国仪精测比表面及孔径分析仪在医药辅料—硬脂酸镁中的应用

文献名： Structural, morphological and optical properties of Bi NPs obtained by laser ablation and their selective detection of L-cysteine 作者： Ramon Gabriel Teixeira Rosaa, Celso de Araujo Duartea , Wido Herwig Schreinera, Ney Pereira Mattoso Filhoa, Arandi Ginane Bezerra Jr.b, Andersson Barisonc, Fernanda Maria Marins Ocamposc a Departamento de Física, Universidade Federal do Paraná Centro Politécnico, CP 19044, 81531-990 Curitiba (PR), Brazil b Departamento Acadêmico de Física, Universidade Tecnológica Federal do Paraná, 80230-901 Curitiba (PR), Brazil c Departamento de Química, Universidade Federal do Paraná Centro Politécnico, CP 19081, 81531-990 Curitiba (PR), Brazil 摘要：In the present work we show the results of the investigation of the properties of bismuth nanoparticles (NPs) obtained by the laser ablation in water. The samples were characterized by various techniques: UV/vis spectroscopy, dynamic light scattering, transmission electron microscopy, X-ray photoelectron spectroscopy, X-ray diffraction, nuclear magnetic resonance and zeta potential. The NPs were metallic and surface oxidated, exhibiting absorption peak at 257 nm due to the surface plasmon resonance. The interaction between the NPs and various amino acids was studied and revealed a selective sensibility to cysteine on a range of concentration from 80 to 720 μM, which we attribute to a dimerization of cysteine to cystine probably complexed to the nanoparticle surface by electrostatic interactions, leading to the modification of the NP absorption spectrum. 关键词：Bismuth; Nanoparticles; Laser ablation; Cysteine

纯水是制备溶出溶剂或生物相关溶液的重要成分，因此水质的好坏会影响结果。一旦水质选择不当，就会引入污染物，主要有以下几种类型。使用高质量纯水来制备溶出溶剂，是获取精确、可重现结果并满足监管要求的重要保障。

市面上有众多的新冠病毒qPCR检测试剂盒，本应用方案采用韩国Seegene公司的AllplexTM 2019-nCoV检测试剂盒在耶拿荧光定量PCR仪 qTOWER³G上进行样品检测，获得符合预期的结果。

当称量仪器用于与质量控制相关的测量时，校准是必须定期执行的关键操作之一。国际上有许多标准规范都有这方面的要求，例如ISO9001、GMP法规以及与食品安全相关的一些标准。然而关于校准的定义、实施和校准的具体操作在全球范围内并没有一个完全统一的标准。在此，我们首先需要了解一下什么是校准，以及与调整和检定的区别。