赛多利斯 ambr® 15 微生物系统

Micro bioreactor, 10-15mL

ambr® 15 fermentation is a new automated microscale bioreactor system designed for microbial applications.

Based on the gold-standard ambr 15 technology, it provides a consistent microscale model for early microbial strain screening with enhanced capabilities supporting fed-batch microbial cultures.

• Increases lab productivity by automating experiment setup, sampling and reagent addition for up to 24 experiments in parallel.

• Enhances scalability over shaken cultures with full control of DO and pH in fed-batch culture, impeller stirring, gas sparging and pumped additions of pH reagent and feed.

• Enables data-rich culture profiles with automated sampling and enough culture volume for many samples during a run.

Features

ambr® 15 fermentation combines 24 single-use micro bioreactor vessels, an automated workstation and user-friendly software:

• Online monitoring and closed-loop control of pH (6-8) and DO, with independent control of N2, O2  and air for each vessel

• Cascade DO control system for gas flow, stirrer speed and gas mixture

• Full control of impeller speed, gas flow rates and bioreactor temperature

• Automated liquid handling for reactor set-up, feeds, base addition and sampling

• Software controls and monitors all experiments and records data and events with a full audit trail.

• Easy installation into laminar flow hood allowing aseptic operation

Vessels

ambr® 15 fermentation vessels mimic the characteristics of a classical lab scale bioreactor:

• Single-use micro bioreactors designed for use with the ambr® 15 fermentation workstation

• Sensors for pH (6-8) and DO for continuous monitoring and control

• Integral impeller for rapid, efficient mixing

• Sparge tube delivers gas to the impeller mixing zone

• 10-15mL working volume (8-12 mL liquid plus gas bubbles) with sample port to allow addition of reagents and feeds or removal of samples

Applications

ambr® 15 fermentation can be used as a microscale model to enhance research in a range of development applications such as:

• Vector screening

• Strain selection

• Media development