简介:A high-performance liquid chromatographic
method, with electrospray ionisation tandem mass spectrometry
(HPLC–ESI–MS–MS) for detection, has been
developed for the determination of thiabendazole, carbendazime,
and phe简介:A high-performance liquid chromatographic
method, with electrospray ionisation tandem mass spectrometry
(HPLC–ESI–MS–MS) for detection, has been
developed for the determination of thiabendazole, carbendazime,
and phenylurea pesticides in fruit matrices. During
the validation process the method was tested for matrix
effects, blanks, and the stability of the system. Considerable
unspecific matrix effects in the ESI (+) process were
detected by comparing standard calibration, and matrix
calibration, although blank values were very low and the
specific calibration functions showed only small standard
deviations. This effect was overcome by using a more complex
clean-up, i.e. an additional size-exclusion step.详细>