简介:GLP (Good Laboratory Practice) requires periodic
checking of the reproducibility and accuracy of
analytical instruments by using Standard Operating
Procedures (SOPs).
This Application Bulletin is intended to provide 简介:GLP (Good Laboratory Practice) requires periodic
checking of the reproducibility and accuracy of
analytical instruments by using Standard Operating
Procedures (SOPs).
This Application Bulletin is intended to provide you
with a guideline for the validation of your Rancimat. A
standard operating procedure is proposed which
allows all the Rancimat functions which are relevant
for the measurement to be checked. The limits given
are to be taken as being examples of what can be
achieved under normal laboratory conditions.
Depending on the demands placed upon the accuracy
of the measuring system, it may be necessary to
redefine these limits in the standard operating
procedure. If very careful work is carried out under
appropriate conditions then it may be possible to
achieve lower limits.
The operating software for the 743 Rancimat contains
prepared GLP tests for the temperature, conductivity
and gas flow measurements. The operator can
determine whether and which tests are to be carried
out, in addition the interval between the tests and the
required accuracy can also be defined. If the GLP
function is activated then a comment will be made on
each result report as to whether the GLP test
requirements have been fulfilled. In order to be able to
carry out the most important tests Metrohm offers the
6.5616.000 GLP Test Set as an option.
Further information about the topics of QA, GLP and
validation can also be found in the brochure "Quality
management with Metrohm" which is available from
your local Metrohm agency.详细>