简介:AQP8抗体/说明书sc-28624Human AQP8 (aquaporin 8) is a 261 amino acid protein that contains 6 membrane-
spanning domains, 2 conserved asn-pro-ala (NPA) motifs, which are characteristic
of MIP (major intrinsic protein) fa简介:AQP8抗体/说明书sc-28624Human AQP8 (aquaporin 8) is a 261 amino acid protein that contains 6 membrane-
spanning domains, 2 conserved asn-pro-ala (NPA) motifs, which are characteristic
of MIP (major intrinsic protein) family members, and 3 N-linked glycosylation
sites. Aquaporins (AQPs) are a large family of integral membrane
water transport channel proteins that facilitate the transport of water through
the cell membrane. This function is conserved in animals, plants and bacteria.
Many isoforms of aquaporin have been identified in mammals, designated
AQP0 through AQP10. Aquaporins are widely distributed and it is not uncommon
for more than one type of AQP to be present in the same cell. Although
most aquaporins are only permeable to water, AQP3, AQP7, AQP9 and one of
the two AQP10 transcripts are also permeable to urea and glycerol. Aquaporins
are involved in renal water absorption, generation of pulmonary secretions,
lacrimation, and the secretion and reabsorption详细>