简介:中文名称:上皮粘连调控蛋白ESRP2 多克隆抗体
英文名字:ESRP2 Polyclonal Antibody
供 应 商:远慕生物
背景资料:ESPR2 is an epithelial cell-type-specific splicing regulator. ESRP2 (Epithelial Splicing Regulatory Protein 2) is简介:中文名称:上皮粘连调控蛋白ESRP2 多克隆抗体
英文名字:ESRP2 Polyclonal Antibody
供 应 商:远慕生物
背景资料:ESPR2 is an epithelial cell-type-specific splicing regulator. ESRP2 (Epithelial Splicing Regulatory Protein 2) is a Protein Coding gene. Among its related pathways are Signaling by FGFR2 and mRNA Capping.
宿主物种:兔
交叉反应:人,小鼠,大鼠,狗,奶牛
克隆类型:多克隆
分 子 量:78kDa
浓 度:1mg/1ml
亚 型:IgG
细胞定位:细胞核
免 疫 原:KLH conjugated synthetic peptide derived from human ESRP2
纯化方法:蛋白A亲和纯化
产品应用:WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复)
尚未测试其他应用;
实际稀释浓度可根据用户的具体用途决定。
储 存 液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol
保存条件:4℃运输,-20℃保存,避免反复冻融
应用领域:细胞生物 细胞粘附分子 细胞类型标志物 表观遗传学
保存建议 自发货之日起,-20°C可稳定保存1年。为最大限度的避免损失,请在打开管盖之前融化抗体并离心。我们建议使用前分装以避免反复冻融。
产品介绍
background:
mRNA splicing factor that regulates the formation of epithelial cell-specific isoforms. Specifically regulates the expression of FGFR2-IIIb, an epithelial cell-specific isoform of FGFR2. Also regulates the splicing of CD44, CTNND1, ENAH, 3 transcripts that undergo changes in splicing during the epithelial-to-mesenchymal transition (EMT). Acts by directly binding specific sequences in mRNAs. Binds the GU-rich sequence motifs in the ISE/ISS-3, a cis-element regulatory region present in the mRNA of FGFR2.
Function:
mRNA splicing factor that regulates the formation of epithelial cell-specific isoforms. Specifically regulates the expression of FGFR2-IIIb, an epithelial cell-specific isoform of FGFR2. Also regulates the splicing of CD44, CTNND1, ENAH, 3 transcripts that undergo changes in splicing during the epithelial-to-mesenchymal transition (EMT). Acts by directly binding specific sequences in mRNAs. Binds the GU-rich sequence motifs in the ISE/ISS-3, a cis-element regulatory region present in the mRNA of FGFR2.
Subcellular Location:
Nucleus.
Tissue Specificity:
Epithelial cell-specific.
Similarity:
Belongs to the ESRP family.
Contains 3 RRM (RNA recognition motif) domains.
Database links:
UniProtKB/Swiss-Prot: Q9H6T0.1
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.详细>