染色体脆弱性相关基因抗体

英文名称    ATAD5    

中文名称    染色体脆弱性相关基因抗体    

别    名    ATPase family AAA domain containing 5; C17orf41; chromosome fragility associated gene 1; FRAG1; Putative uncharacterized protein Fragment.    

说 明 书    0.2ml      

研究领域    细胞生物  染色质和核信号  细胞凋亡  细胞周期蛋白  表观遗传学      

抗体来源    Rabbit    

克隆类型    Polyclonal    

交叉反应    Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Rabbit,     

产品应用    WB=1:100-500 ELISA=1:500-1000 IP=1:20-100 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 染色体脆弱性相关基因抗体（石蜡切片需做抗原修复） 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.    

分 子 量    203kDa    

细胞定位    细胞核     

性    状    Lyophilized or Liquid    

浓    度    1mg/1ml    

免 疫 原    KLH conjugated synthetic peptide derived from human ATAD5    

亚    型    IgG    

纯化方法    affinity purified by Protein A    

储 存 液    Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4    

保存条件    Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.    

染色体脆弱性相关基因抗体产品介绍    background:

ATAD5 is a homolog of a subunit of RFC (replication factor C) and has been shown to be down-regulated in response to replicative stress. ATAD5 may play a role in the surveillance of DNA damage and the cell’s decision to survive or activate apoptosis.

Subunit:
"Interacts with RB1 predominantly in G1 phase via its LXCXE motif. Interacts with RAD9A in growing cells. The interaction with RAD9A is reduced after exposure to DNA replication-inhibiting agents.

Subcellular Location:
Nucleus.

Similarity:
Belongs to the AAA ATPase family.

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.    

染色体脆弱性相关基因抗体

hz-0318P PADI4 (HL-60 PAD)(Protein-arginine deiminase type IV，PADI 4，PAD I4 )  关节炎相关基因

hz-0196P PDGF-A  血小板源性生长因子-1（抗原）

hz-0185P PDGF-B  血小板源性生长因子-B（抗原）

hz-0231P PDGF-R-A  血小板源性生长因子受体-A（抗原）

hz-0232P PDGF-R-B  血小板源性生长因子受体-B（抗原）

hz-0235P PMP-22(Peripheral Myelin Protein)  外周髓鞘蛋白-22多肽

hz-0128P PI3K  磷脂酰肌醇激酶（抗原）

hz-1374P BMP4(bone morphogenetic protein 4)  骨形态发生蛋白4（抗原）

hz-0234P PLGF (Placenta growth factor)  小鼠胎盘生长因子（多肽抗原）

hz-0280P PLGF (Placenta growth factor)  胎盘生长因子（多肽抗原）

hz-0281P PLGF (Placenta growth factor fragment)(human)  人胎盘生长因子（多肽抗原）

hz-0133P PP-1  蛋白磷酸酯酶-1（抗原）

hz-1509P BMPR-1A(Bone Morphogenetic protein Receptor-1A)  骨成型蛋白受体1A抗原

hz-0250P PPAR-delta (peroxisome proliferator-activated receptor)  D型-过氧化酶活化增生受体(多肽）

hz-0029P PP-2A (protein phosphatase 2A)  蛋白质磷酸酶-2A（抗原）

hz-1418P BOb-1(B-cell oct-binding protein 1)  B细胞特异性转录因子抗原

hz-0030P PP-2B alpha 1   蛋白磷酸酯酶-2B 催化亚单位（抗原）

hz-0111P PR (Progestogerone receptor)  孕激素受体（抗原）

hz-0024P PS-1(NT)，Presennillin-1(S182)  早老素蛋白-1（抗原）

hz-0025P PS-1，Presennillin-1(CT)  早老素蛋白-1（S182）

hz-0803P BRCA1(Breast cancer susceptbility gene 1)(mouse rat)  乳腺癌易感基因1抗原(小鼠 大鼠)

hz-0802P BRCA1  乳腺癌易感基因1抗原

hz-0179P PSD-95   突触后密度蛋白95（抗原）

hz-1210P BRCA2(Breast cancer susceptbility gene 2)  乳腺癌易感基因2抗原

hz-0182P PTP-1B (Protein-tyrosine phosphatase, non-receptor )  蛋白酪氨酸磷酸酶-1B（抗原）

hz-0251P RAR-Alpha (Retinoic acid -R-Alpha)  维甲酸受体-α 多肽

hz-0319P glycoprotein (E1 glycoprotein) [Rubella virus]  风疹病毒糖蛋白多肽片段

hz-0121P SAP-1 (Synapse associated protein-I) peptide  突触相关蛋白-1（多肽抗原）

hz-0130P SARS S-protein(抗原)  

hz-0132P SARS putative orflab polyprotein (SARS coronavirus CUHK-W1)(抗原)  

hz-4813-P 禽流感H5亚型全病毒抗原  H5N1-H5

hz-1954P BSEP peptide  胆汁酸盐输出泵蛋白抗原

hz-0088P Secretin  分泌素（抗原）

hz-0089P Secretin receptor  分泌素受体（抗原）