EGF毒素受体7跨膜结构域蛋白1抗体

英文名称    ETL    

中文名称    EGF毒素受体7跨膜结构域蛋白1抗体    

别    名    EGF; EGF latrophilin and seven transmembrane domain containing 1; EGF TM7 latrophilin related protein; EGF-TM7-latrophilin-related protein; EGFTM7 latrophilin related protein; ELTD 1; ELTD1; ELTD1_HUMAN; ETL; ETL protein; KPG_003; latrophilin and seven transmembrane domain-containing protein 1; zgc:63629.    

说 明 书    0.1ml  0.2ml      

研究领域    细胞生物  信号转导  G蛋白偶联受体  G蛋白信号  跨膜蛋白      

抗体来源    Rabbit    

克隆类型    Polyclonal    

交叉反应    Human, Mouse, Rat, Horse,     

产品应用    WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 Flow-Cyt=1:100-500 ICC=1:100-500 IF=1:100-500 EGF毒素受体7跨膜结构域蛋白1抗体（石蜡切片需做抗原修复） 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.    

细胞定位    细胞膜     

性    状    Lyophilized or Liquid    

浓    度    1mg/1ml    

免 疫 原    KLH conjugated synthetic peptide derived from human ETL/ELTD1    

亚    型    IgG    

纯化方法    affinity purified by Protein A    

储 存 液    Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4    

保存条件    Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.    

EGF毒素受体7跨膜结构域蛋白1抗体产品介绍    background:

The epidermal growth factor (EGF)-TM7 family constitutes a group of leukocyte-restricted, class B G-protein coupled receptors (GPCRs). These include CD97, EMR1(EGF-like molecule containing mucin-like hormone receptor 1, designated F4/80 in mouse), EMR2, EMR3, FIRE, and ETL. These family members are characterized by an extended extracellular region with several N-terminal EGF domains and are predominantly expressed on cells of the immune system. Unlike other GPCRs, neither EMR2 nor EMR3 have mouse orthologs. The molecular twins CD97 and EMR2 only differ by 6 out of 236 amino acids, but this slight difference is enough to alter ligand specificity and confer nonredundant functions. EMR3 may function in myeloid-myeloid interactions during immune and inflammatory responses. ETL is a 738 amino acid protein composed of a large extracellular domain with EGF-like repeats, a seven-transmembrane domain, and a short cytoplasmic tail. ETL mRNA expression is up-regulated in the adult rat and human heart.

Function:
Could be involved in cardiac development.

Subunit:
Forms a heterodimer, consisting of a large extracellular region (alpha subunit) non-covalently linked to a seven-transmembrane moiety (beta subunit). Forms stable dimer at the cells surface (By similarity).

Subcellular Location:
Cell membrane.

Tissue Specificity:
Mainly expressed in smooth muscle.

Post-translational modifications:
Proteolytically cleaved into 2 subunits, an extracellular alpha subunit and a seven-transmembrane subunit.

Similarity:
Belongs to the G-protein coupled receptor 2 family. LN-TM7 subfamily.
Contains 2 EGF-like domains.
Contains 1 GPS domain.    

EGF毒素受体7跨膜结构域蛋白1抗体

hz-0277P Tanis/SELS (Selenoprotein S)又称SELS  炎症负调控因子蛋白（抗原）

hz-0157P Tau protein  微管相关蛋白（抗原）

hz-0233P Telomerase (TE)  端粒酶（催化亚单位）（多肽抗原）

hz-0066P TGF-Alpha (Ttansforming Growth Factor –Alpha)  转移生长因子–α（抗原）

hz-0564P CaMK2a(calcium/calmodulin-dependent protein kinase II alpha)  钙/钙调素依赖蛋白激酶2α抗原

hz-1809P Camk1g(Calcium/calmodulin dependent protein kinase IG)  钙/钙调蛋白依赖蛋白激酶IG抗原

hz-0103P TGF- Beta1 (Ttansforming Growth Factor – Beta1)  转移生长因子–β1（抗原）

hz-0541P CaMK2b(calcium/calmodulin-dependent protein kinase II beita)  钙/钙调素依赖蛋白激酶2b抗原

hz-1306P CAP1/Park7/DJ-1  Park7/DJ-1/CAP1抗原

hz-1616P CAP2(Adenylyl cyclase-associated protein 2)  环化酶相关蛋白CAP-2抗原

hz-0100P TGF beta 2 Propeptide  转移生长因子–β2前体肽

hz-0099P TGF- Beta3 (Ttansforming Growth Factor – Beta3)  转移生长因子–β3（抗原）

hz-0117P TGF- Beta R2 peptide  转移生长因子β受体2（多肽抗原）

hz-0226P Thymosin Alpha-1  胸腺肽 α-1 （胸腺肽-Thymosin alpha-1）

hz-1105P Caspase-12  半胱胺酸蛋白酶蛋白-12(多肽)

hz-0967P Caspase-12(hunman)  半胱胺酸蛋白酶蛋白-12抗原(人)

hz-0054P TmR2(GDNFR Beta；TRN-R；GFR-alpha-2；NTNR-2)  胶质细胞系源性神经营养因子（多肽）

hz-0078P TNF-Alpha(Tumor Necrosis Factor-Alpha)  人肿瘤坏死因子-α（多肽抗原）

hz-0387P rh-TNF-Alpha(rh-Tumor Necrosis Factor alpha)  重组人肿瘤坏死因子

hz-2258P rh-TNF alpha protein GST Tagged  重组人肿瘤坏死因子

hz-0328P TRA16  睾丸激素受体相关蛋白

hz-0884P rh-IL-1Ra(Recombinant Human Interleukin-1 receptor antagonist His Tag)  重组人白介素-1受体拮抗剂

hz-0514P rhBMP-2/BMP2  重组人骨形态发生蛋白-2

hz-0504P rh-BMP-7/BMP7(bone morphogenetic protein-7,BMP-7;rhBMP-7)  重组人骨形态发生蛋白7

hz-2033P E.coli DH-5 Alpha(E.coli DH-5 Alpha Protein)  DH 5 alpha 大肠杆菌菌体蛋白

hz-0152P Tranthyretin  甲状腺素运载蛋白（抗原）

hz-2050P rh-EGF(Recombinant Epidermal growth factor)  重组人表皮生长因子

hz-0193P TrK A (h-NGFR) (p140- TrK A)  神经生长因子的一种（抗原）

hz-1637P rh-VEGF(GST Tag)(Recombinant Vascuoar endothelial growth factor)  重组人血管内皮细胞生长因子

hz-0192P TrK A.B.C   神经生长因子的一种（抗原）

hz-0087P active Caspase 3(caspase-3 p12 subunit)  活化半胱胺酸蛋白酶蛋白-3抗原

hz-2122P r-GST(Recombinant Glutathione S-T Ahents)  重组谷胱甘肽转移酶GST标签蛋白