英文名称 ENT1
中文名称 核苷转运蛋白ENT1抗体
别 名 Equilibrative NBMPR-sensitive nucleoside transporter; equilibrative nitrobenzylmercaptopurine riboside (NBMPR)-sensitive nucleoside transporter; Equilibrative nitrobenzylmercaptopurine riboside-sensitive nucleoside transporter; Equilibrative nucleoside transporter 1; es-type; MGC1465; MGC3778; Nucleoside transporter; Nucleoside transporter, es-type; OTTHUMP00000016506; OTTHUMP00000016507; OTTHUMP00000016508; OTTHUMP00000016509; OTTHUMP00000016510; OTTHUMP00000016511; OTTHUMP00000016512; S29A1_HUMAN; SLC29A1; solute carrier family 29 (nucleoside transporters), member 1; Solute carrier family 29 member 1.
说 明 书 0.2ml
研究领域 肿瘤 细胞生物 信号转导 新陈代谢
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Human, Mouse, Rat, Cow, Horse, Sheep, Cynomolgus Monkey, Orangutan
产品应用 WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 核苷转运蛋白ENT1抗体(石蜡切片需做抗原修复)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 50kDa
细胞定位 细胞膜
性 状 Lyophilized or Liquid
浓 度 1mg/1ml
免 疫 原 KLH conjugated synthetic peptide derived from human ENT1/SLC29A1
亚 型 IgG
纯化方法 affinity purified by Protein A
储 存 液 Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
核苷转运蛋白ENT1抗体产品介绍 background:
Equilibrative nucleoside transporters (ENTs) regulate many physiological processes and are widely distributed in mammals, plants, yeasts, insects, nematodes and protozoans. They enable facilitated diffusion of hydrophilic nucleosides, such as adenosine and nucleoside analogs, across cell membranes. ENTs are required for uptake of antiviral and anticancer nucleoside drugs and influence a variety of physiological processes, such as neurotransmission and platelet aggregation, by regulating the amount of adenoside available to cell surface receptors. Equilibrative nucleoside transporter 1 (ENT1), also designated solute carrier family 29 (nucleoside transporters), member 1, belongs to the SLC29A transporter family and is a mammalian ENT isoform. ENT1, along with ENT3, mediates the majority of influx and efflux of nucleosides across the plasma membrane.
Function:
Mediates both influx and efflux of nucleosides across the membrane (equilibrative transporter). It is sensitive (ES) to low concentrations of the inhibitor nitrobenzylmercaptopurine riboside (NBMPR) and is sodium-independent. It has a higher affinity for adenosine. Inhibited by dipyridamole and dilazep (anticancer chemotherapeutics drugs).
Subcellular Location:
Basolateral cell membrane. Apical cell membrane. Predominantly localized in the basolateral membrane in polarised MDCK cells.
Tissue Specificity:
Expressed in heart, brain, mammary gland, erythrocytes and placenta, and also in fetal liver and spleen.
Post-translational modifications:
Glycosylated.
Similarity:
Belongs to the SLC29A transporter family.
核苷转运蛋白ENT1抗体
hz-0345R-FIThz Rabbit Anti-human IgM/FITC FITC标记的兔抗人IgM
hz-0345R-hzy3 Rabbit Anti-human IgM/Cy3 Cy3标记的兔抗人IgM
hz-0345R-hzy5 Rabbit Anti-human IgM/Cy5 Cy5标记的兔抗人IgM
hz-0345R-hzy5.5 Rabbit Anti-human IgM/Cy5.5 Cy5.5标记的兔抗人IgM
hz-0345R-hzy7 Rabbit Anti-human IgM/Cy7 Cy7标记的兔抗人IgM
hz-0345R-PE Rabbit Anti-human IgM/PE PE标记的兔抗人IgM
hz-0345R-PE-hzy3 Rabbit Anti-human IgM/PE-Cy3 PE-Cy3标记的兔抗人IgM
hz-0345R-PE-hzY5 Rabbit Anti-human IgM/PE-CY5 PE-CY5标记的兔抗人IgM
hz-0345R-APhz Rabbit Anti-human IgM/APC APC标记的兔抗人IgM
hz-0345R-AF350 Rabbit Anti-human IgM/Alexa Fluor 350 Alexa Fluor 350标记的兔抗人IgM
hz-0345R-AF488 Rabbit Anti-human IgM/Alexa Fluor 488 Alexa Fluor 488标记的兔抗人IgM
hz-0345R-AF555 Rabbit Anti-human IgM/Alexa Fluor 555 Alexa Fluor 555标记的兔抗人IgM
hz-0345R-AF647 Rabbit Anti-human IgM/Alexa Fluor 647 Alexa Fluor 647标记的兔抗人IgM
hz-0345R-PE-hzy5.5 Rabbit Anti-human IgM/PE-Cy5.5 PE-Cy5.5标记的兔抗人IgM
hz-0345R-PE-hzy7 Rabbit Anti-human IgM/PE-Cy7 PE-Cy7标记的兔抗人IgM
hz-0345R-Gold Rabbit Anti-human IgM/Gold 胶体金标记的兔抗人IgM
hz-0345R-AP Rabbit Anti-human IgM/AP 碱性磷酸酶(AP)标记的兔抗人IgM
hz-0345R-RBIThz Rabbit Anti-human IgM/RBITC 罗丹明标记的兔抗人IgM
hz-0345R-Bio Rabbit Anti-human IgM/Bio 生物素标记的兔抗人IgM
hz-0345R-HRP Rabbit Anti-human IgM/HRP 辣根过氧化物酶标记的兔抗人IgM
hz-0360R-HRP Rabbit Anti-human sIgA/HRP 辣根过氧化物酶标记兔抗人IgA
hz-0360R-Bio Rabbit Anti-human sIgA/Bio 生物素标记的兔抗人分泌型IgA
hz-0360R-Gold Rabbit Anti-human sIgA/Gold 胶体金标记的兔抗人分泌型IgA
hz-0360R-hzy3 Rabbit Anti-human sIgA/Cy3 Cy3标记的兔抗人分泌型IgA
hz-0360R-hzy5 Rabbit Anti-human sIgA/Cy5 Cy5标记的兔抗人分泌型IgA
hz-0360R-hzy5.5 Rabbit Anti-human sIgA/Cy5.5 Cy5.5标记的兔抗人分泌型IgA
hz-0360R-hzy7 Rabbit Anti-human sIgA/Cy7 Cy7标记的兔抗人分泌型IgA
hz-0360R-PE Rabbit Anti-human sIgA/PE PE标记的兔抗人分泌型IgA
hz-0360R-PE-hzy3 Rabbit Anti-human sIgA/PE-Cy3 PE-Cy3标记的兔抗人分泌型IgA
hz-0360R-PE-hzY5 Rabbit Anti-human sIgA/PE-CY5 PE-CY5标记的兔抗人分泌型IgA
hz-0360R-APhz Rabbit Anti-human sIgA/APC APC标记的兔抗人分泌型IgA
hz-0360R-AF350 Rabbit Anti-human sIgA/Alexa Fluor 350 Alexa Fluor 350标记的兔抗人分泌型IgA
hz-0360R-AF488 Rabbit Anti-human sIgA/Alexa Fluor 488 Alexa Fluor 488标记的兔抗人分泌型IgA
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