对接蛋白EFS抗体

英文名称    EFS    

中文名称    对接蛋白EFS抗体    

别    名    CAS3; CASS3; EFS1; EFS2; Embryonal Fyn associated substrate; HEFS; SIN; EFS_HUMAN.    

说 明 书    0.1ml  0.2ml      

研究领域    细胞生物  细胞粘附分子      

抗体来源    Rabbit    

克隆类型    Polyclonal    

交叉反应    Human, Mouse, Rat, Pig, Cow, Sheep,     

产品应用    WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 对接蛋白EFS抗体（石蜡切片需做抗原修复） 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.    

分 子 量    59kDa    

细胞定位    细胞浆     

性    状    Lyophilized or Liquid    

浓    度    1mg/1ml    

免 疫 原    KLH conjugated synthetic peptide derived from human EFS    

亚    型    IgG    

纯化方法    affinity purified by Protein A    

储 存 液    Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4    

保存条件    Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.    

对接蛋白EFS抗体产品介绍    background:

EFS is a docking protein which plays a pivotal role for cell adhesion-related intracellular tyrosine kinase signaling, where it may serve as an activator of SRC and is known to interat with the SH3 domain of FYN and with CRK, SRC, and YES.

Function:
Docking protein which plays a central coordinating role for tyrosine-kinase-based signaling related to cell adhesion. May serve as an activator of SRC and a downstream effector. Interacts with the SH3 domain of FYN and with CRK, SRC, and YES (By similarity). 

Subcellular Location:
Cytoplasm

Tissue Specificity:
The protein has been detected in lung and placenta.

Post-translational modifications:
Phosphorylated on multiple tyrosine residues. Phosphorylated on tyrosines by FYN and SRC (By similarity).

Similarity:
Belongs to the CAS family. 
Contains 1 SH3 domain. 

Database links:
UniProtKB/Swiss-Prot: O43281.1

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.    

对接蛋白EFS抗体

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