DNA损伤自噬调整蛋白抗体

英文名称    DRAM    

中文名称    DNA损伤自噬调整蛋白抗体    

别    名    Damage regulated autophagy modulator; Damage-regulated autophagy modulator; DNA damage-regulated autophagy modulator protein 1; dram1; DRAM1_HUMAN.    

说 明 书    0.1ml  0.2ml      

研究领域    肿瘤  心血管  免疫学  细胞凋亡      

抗体来源    Rabbit    

克隆类型    Polyclonal    

交叉反应    Human, Mouse, Rat, Dog, Pig, Horse, Rabbit, Sheep,     

产品应用    WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 DNA损伤自噬调整蛋白抗体（石蜡切片需做抗原修复） 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.    

分 子 量    26kDa    

细胞定位    细胞浆 细胞膜     

性    状    Lyophilized or Liquid    

浓    度    1mg/1ml    

免 疫 原    KLH conjugated synthetic peptide derived from human DRAM    

亚    型    IgG    

纯化方法    affinity purified by Protein A    

储 存 液    Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4    

保存条件    Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.    

DNA损伤自噬调整蛋白抗体产品介绍    background:

This gene is regulated as part of the p53 tumor suppressor pathway. The gene encodes a lysosomal membrane protein that is required for the induction of autophagy by the pathway. Decreased transcriptional expression of this gene is associated with various tumors. This gene has a pseudogene on chromosome 4. [provided by RefSeq, Jul 2008]

Function:
Lysosomal modulator of autophagy that plays a central role in p53/TP53-mediated apoptosis. Not involved in p73/TP73-mediated autophagy.

Subcellular Location:
Lysosome membrane; Multi-pass membrane protein.

Similarity:
Belongs to the DRAM/TMEM150 family.

Gene ID:
55332

Database links:

Entrez Gene: 55332 Human

Entrez Gene: 71712 Mouse

Omim: 610776 Human

SwissProt: Q8N682 Human

SwissProt: Q9DC58 Mouse

Unigene: 525634 Human

Unigene: 35450 Mouse

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.    

DNA损伤自噬调整蛋白抗体

hz-9081R AKIRIN1  AKIRIN1蛋白抗体

hz-9082R AKIRIN2  AKIRIN2蛋白抗体

hz-9083R FBXW5  FBXW5蛋白抗体

hz-9084R FBXW12/FBXO35  FBXW12蛋白抗体

hz-9085R FBXO42  FBXO42蛋白抗体

hz-9087R FBXO4  FBXO4蛋白抗体

hz-9088R FBXO28  FBXO28蛋白抗体

hz-9089R FBXO27  FBXO27蛋白抗体

hz-9090R FBXO24  FBXO24蛋白抗体

hz-9091R hnRNP A2B1  异质核糖核蛋白hnRNPA2抗体

hz-9092R hnRNP U  异质核糖核蛋白U抗体

hz-9093R AIM1L  黑色素瘤缺失样蛋白1抗体

hz-9094R AHNAK2  AHNAK核蛋白2抗体

hz-9095R AGXT2L2  AGXT2L2蛋白抗体

hz-9096R AER61  未知糖基化转移酶AER61抗体

hz-9097R ANKS1B/AIDA1  β淀粉样蛋白胞内结构域相关蛋白1抗体

hz-9098R ANKS3  锚蛋白重复及SAM结构域蛋白3抗体

hz-9099R ANKS6  锚蛋白重复及SAM结构域蛋白6抗体

hz-9100R ARSF  芳香基硫酸酯酶F抗体

hz-9101R ARSH  芳香基硫酸酯酶H抗体

hz-9102R ARSK  芳香基硫酸酯酶K抗体

hz-9103R ART3  二磷酸腺苷核糖基转移酶3抗体

hz-9104R Tankyrase  端粒调控因子抗体

hz-9105R ART5  二磷酸腺苷核糖基转移酶5抗体

hz-9106R ASB13  含锚蛋白重复序列-细胞因子信号抑制物盒蛋白家族13抗体

hz-9107R ASC2/POP1  感染性蛋白唯一蛋白1抗体

hz-9108R ATAD3A/B/C  三磷酸腺苷酶家族蛋白3A抗体

hz-9109R MAP4K6/MINK1  丝裂原活化蛋白激酶MAP4K6抗体

hz-9110R ATAD2  三磷酸腺苷酶家族蛋白2抗体

hz-9112R ASMTL  ASMTL蛋白抗体

hz-9113R GPCR TAS1R3  G蛋白偶联受体TAS1R3抗体

hz-9114R BAGE2  肿瘤/睾丸抗原2.2抗体

hz-9115R BAGE3  肿瘤/睾丸抗原2.3抗体