细胞周期检测点激酶1抗体

英文名称    CHK1    

中文名称    细胞周期检测点激酶1抗体    

别    名    Cell cycle checkpoint kinase; Checkpoint, S. pombe, homolog of, 1; Checkpoint kinase 1; Checkpoint kinase 1 homolog (S. pombe); CHEK 1; CHEK-1; CHEK1; Chk 1; Chk1; CHK1 checkpoint homolog (S. pombe); EC 2.7.11.1; rad27; Serine/threonine protein kinase Chk1; Serine/threonine-protein kinase CHK1; STT3, subunit of the oligosaccharyltransferase complex, homolog A (S. cerevisiae); C85740; CHK1_HUMAN.    

说 明 书    0.2ml      

研究领域    肿瘤  染色质和核信号  细胞周期蛋白  激酶和磷酸酶      

抗体来源    Rabbit    

克隆类型    Polyclonal    

交叉反应    Human, Mouse, Rat,     

产品应用    WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 细胞周期检测点激酶1抗体（石蜡切片需做抗原修复） 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.    

分 子 量    54kDa    

细胞定位    细胞核 细胞浆     

性    状    Lyophilized or Liquid    

浓    度    1mg/1ml    

免 疫 原    KLH conjugated synthetic peptide derived from human CHK1    

亚    型    IgG    

纯化方法    affinity purified by Protein A    

储 存 液    0.01M PBS, pH 7.4 with 10 mg/ml BSA and 0.1% Sodium azide    

保存条件    Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.    

细胞周期检测点激酶1抗体产品介绍    background:

The protein encoded by this gene belongs to the Ser/Thr protein kinase family. It is required for checkpoint mediated cell cycle arrest in response to DNA damage or the presence of unreplicated DNA. This protein acts to integrate signals from ATM and ATR, two cell cycle proteins involved in DNA damage responses, that also associate with chromatin in meiotic prophase I. Phosphorylation of CDC25A protein phosphatase by this protein is required for cells to delay cell cycle progression in response to double-strand DNA breaks. Several alternatively spliced transcript variants have been found for this gene.[provided by RefSeq, Oct 2011].    

细胞周期检测点激酶1抗体

hz-3546R RIP2  受体结合丝氨酸苏氨酸激酶2抗体

hz-3361R Phospho-RIP2 (Ser176)  磷酸化受体结合丝氨酸苏氨酸激酶2抗体

hz-3551R RIPK3  受体结合丝氨酸苏氨酸激酶3抗体

hz-3564R RICTOR  雷帕霉素靶蛋白复合体2抗体

hz-3387R Phospho-Rictor (Thr1135)  磷酸化雷帕霉素靶蛋白复合体2抗体

hz-2125R RNF126  环指蛋白126抗体

hz-2163R RNF148  环指蛋白148抗体

hz-6096R RNF139  环指蛋白139抗体

hz-4104R FXYD1  磷酸神经膜抗体

hz-1166R ROCK1  Rho相关蛋白激酶1抗体

hz-4630R phospho-ROCK1(Thr455/Ser456)  磷酸化Rho相关蛋白激酶1抗体

hz-1205R ROCK2  Rho相关蛋白激酶2抗体

hz-5674R phospho-ROCK2(Thr396)  磷酸化Rho相关蛋白激酶2抗体

hz-5675R phospho-ROCK2(Thr249)  磷酸化Rho相关蛋白激酶2抗体

hz-5676R phospho-ROCK2(Tyr256)  磷酸化Rho相关蛋白激酶2抗体

hz-1886R RPLP0  酸性核糖体磷蛋白大亚基P0抗体

hz-2504R ROS/c ros  活性氧簇ROS抗体

hz-3863R ROR Gamma/RORC/NR1F3  孤儿核受体抗体

hz-3565R RPS6  S6核糖体蛋白抗体

hz-3388R Phospho-S6 Ribosomal Protein (Ser235+Ser236)  磷酸化S6核糖体蛋白抗体

hz-3389R Phospho-S6 Ribosomal Protein (Ser240/244)  磷酸化S6核糖体蛋白抗体

hz-2777R Rb/P105 RB  成视网膜细胞瘤基因抗体

hz-1347R phospho-Rb/p105-Rb(Ser780)  磷酸化成视网膜细胞瘤抑癌蛋白抗体

hz-5348R phospho-FXYD1 (Ser83)  磷酸化磷酸神经膜抗体

hz-0278R RRAD  RRAD抗体

hz-5349R phospho-FXYD1 (Ser88)  磷酸化磷酸神经膜抗体

hz-3554R Rsk2/MAPKAP Kinase 1b  核糖体S6激酶RSK2抗体

hz-3367R Phospho-RSK2 (Ser227)  磷酸化核糖体S6激酶RSK2抗体

hz-3368R Phospho-RSK2(Tyr529)  磷酸化核糖体S6激酶RSK2抗体

hz-3553R RSK3/Ribosomal S6 kinase 3  核糖体蛋白S6激酶家族RSK3抗体