微管蛋白β辅助因子D抗体

英文名称    Beta tubulin cofactor D    

中文名称    微管蛋白β辅助因子D抗体    

别    名    Beta tubulin cofactor D; Beta-tubulin cofactor D; KIAA0988; SSD 1; SSD-1; SSD1; tbcd; TBCD_HUMAN; tfcD; Tubulin folding cofactor D; Tubulin specific chaperone D; Tubulin-folding cofactor D; Tubulin-specific chaperone D.    

说 明 书    0.2ml      

研究领域    肿瘤  细胞生物  信号转导  细胞周期蛋白  细胞骨架  细胞外基质      

抗体来源    Rabbit    

克隆类型    Polyclonal    

交叉反应    Human, Mouse, Rat, Chicken, Rabbit,     

产品应用    WB=1:100-500 ELISA=1:500-1000 IP=1:20-100 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 微管蛋白β辅助因子D抗体（石蜡切片需做抗原修复） 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.    

分 子 量    133kDa    

细胞定位    细胞浆 细胞膜     

性    状    Lyophilized or Liquid    

浓    度    1mg/1ml    

免 疫 原    KLH conjugated synthetic peptide derived from human TBCD/Beta tubulin cofactor D    

亚    型    IgG    

纯化方法    affinity purified by Protein A    

储 存 液    Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4    

保存条件    Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.    

微管蛋白β辅助因子D抗体产品介绍    background:

Tubulin-folding protein; involved in the first step of the tubulin folding pathway. Modulates microtubule dynamics by capturing GTP-bound beta-tubulin (TUBB). Acts as a GTPase-activating protein (GAP) for ARL2. Its ability to interact with beta tubulin is regulated via its interaction with ARL2. Induces microtubule disruption in absence of ARL2. Increases degradation of beta tubulin, when overexpressed in polarized cells. Promotes epithelial cell detachment, a process antagonized by ARL2. Induces tight adherens and tight junctions disassembly at the lateral cell membrane.

Function:
Tubulin-folding protein; involved in the first step ofthe tubulin folding pathway. Modulates microtubule dynamics bycapturing GTP-bound beta-tubulin (TUBB). Acts as aGTPase-activating protein (GAP) for ARL2. Its ability to interactwith beta tubulin is regulated via its interaction with ARL2.Induces microtubule disruption in absence of ARL2. Increasesdegradation of beta tubulin, when overexpressed in polarized cells.Promotes epithelial cell detachment, a process antagonized by ARL2.Induces tight adherens and tight junctions disassembly at thelateral cell membrane.     

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hz-2135P FABP(brain) (Fatty acid-binding protein brain)  脑型脂肪酸结合蛋白抗原

hz-0511P FADD (Fas-associated protein with death domain)  Fas死亡结构域相关蛋白抗原

hz-1340P FAK(Focaladhesin kinase)  粘着斑激酶抗原

hz-1639P phospho-FAK(pTyr577)  磷酸化粘着斑激酶抗原

hz-1642P phospho-FAK(pSer732)(phospho-Focal adhesion kinase)  磷酸化粘着斑激酶抗原

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hz-1256P FGF4/HSTF1/HBGF-4(Fibroblast Growth Factor4)  纤维母细胞生长因子4抗原

hz-1257P FGF5 peptide  纤维母细胞生长因子5抗原

hz-0809P Fibulin 1  衰老关键蛋白抗原

hz-1462P FLG(filaggrin)peptide  丝聚蛋白/中间丝蛋白抗原

hz-1170P FOS B  FosB抗原

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hz-2585P FOXF1(Forkhead box protein F1)  叉头蛋白F1抗原

hz-1775P FOXJ1/HFH-4 peptide  插头蛋白J1抗原

hz-1275P FoxP1(Forkhead box P1)  FoxP1（T细胞转录因子）抗原

hz-2687P FOXM1/HFH 11 peptide  插头蛋白M1抗原

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