原钙粘附蛋白α8抗体

公司钙粘蛋白相关神经受体8抗体具有高纯度、高效价、高特异性的特点，仅用于科学研究，不可用于临床诊断及药物治疗，可以应用于多种实验。CST、Santa抗体品牌。

英文名称  Anti-PCDHA10/CNRN8 

中文名称  钙粘蛋白相关神经受体8抗体 

别    名  Cadherin related neuronal receptor 8; CNR 8; Cnr3; CNR8; CNRN 8; CNRN-8; CNRS 8; CNRS8; CRNR 8; Crnr3; CRNR8; Ortholog to mouse CNR8; PCDH alpha10; PCDHA 10; Pcdha14; PCDHALPHA10; Protocadherin alpha 10; rCNRv10; PCDAA_HUMAN. 

浓    度  1mg/1ml 

规 格  0.2ml/200μg
钙粘蛋白相关神经受体8抗体的相关产品:

Rabbit Anti-Guinea pig IgG/Alexa Fluor 647  Alexa Fluor 647标记的兔抗豚鼠IgG 0.1ml

Rabbit Anti-Guinea pig IgG/AP  碱性磷酸酶（AP）标记的兔抗豚鼠IgG 0.1ml

Rabbit Anti-Guinea pig IgG/APC  APC标记的兔抗豚鼠IgG 0.1ml 

钙粘蛋白相关神经受体8抗体抗体来源  Rabbit  

克隆类型  polyclonal 

交叉反应  Human, Mouse, Rat, Chicken, Zebrafish  

产品类型  一抗    

研究领域  神经生物学 信号转导 细胞粘附分子 细胞骨架  

蛋白分子量  predicted molecular weight: 100kDa 

性    状  Lyophilized or Liquid 

免 疫 原  KLH conjugated synthetic peptide derived from human PCDHA10/CNRN8 

亚    型  IgG 

纯化方法  affinity purified by Protein A 

储 存 液  Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4 

产品应用   WB=1:100-500  ELISA=1:500-1000  IHC-P=1:100-500  IHC-F=1:100-500  Flow-Cyt=1:100-500  ICC=1:100-500  IF=1:100-500 

（石蜡切片需做抗原修复） 

 not yet tested in other applications.

 optimal dilutions/concentrations should be determined by the end user.  

保存条件  Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. 

Important Note  This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. 

产品介绍 Protocadherins are a large family of cadherin-like cell adhesion proteins that are involved in the establishment and maintenance of neuronal connections in the brain. There are three protocadherin gene clusters, designated alpha, beta and gamma, all of which contain multiple tandemly arranged genes. These genes generate thousands of different protocadherin proteins through alternative promoter usage and cis-alternative splicing. PCDHA and PCDHG family members form oligomers, which also increases the diversity of PCDH proteins at the cell surface. All three gene clusters, PCDHA, PCDHB, and PCDHG show upregulated expression during brain development, and PCDHA is subsequently downregulated by myelination. Expression of all three clusters continues in the olfactory bulb, hippocampus and cerebellum until adulthood. Members of the PCDH family are potential targets in schizophrenia and bipolar disorder pathogenesis. PCDHA10 produces at least three isoforms by alternative splicing.

Function : Potential calcium-dependent cell-adhesion protein. May be involved in the establishment and maintenance of specific neuronal connections in the brain.

钙粘蛋白相关神经受体8抗体Subcellular Location : Cell membrane; Single-pass type I membrane protein. Isoform 2: Secreted.

Similarity : Contains 6 cadherin domains. 

Database links : UniProtKB/Swiss-Prot: Q9Y5I2.1

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