公司核蛋白4抗体(Ran结合蛋白4)具有高纯度、高效价、高特异性的特点,仅用于科学研究,不可用于临床诊断及药物治疗,可以应用于多种实验。CST、Santa抗体品牌。
英文名称 Anti-Importin4/RanBP4
中文名称 核蛋白4抗体(Ran结合蛋白4)
别 名 Imp4; Imp4b; Importin 4b; Importin-4; Importin-4b; Ipo4; IPO4_HUMAN; Ran binding protein 4; Ran-binding protein 4; RanBP4; IPO4_HUMAN.
浓 度 1mg/1ml
规 格 0.2ml/200μg
核蛋白4抗体(Ran结合蛋白4)的相关产品:
Anti-β-catenin/β-cats β-连环蛋白抗体 0.1ml
Anti-β-HCG 鼠抗人β亚基人绒毛膜促性腺激素单抗 0.1ml
Anti-γ-Adaptin 衔接蛋白γ抗体 0.1ml
Anti-κOR kappa型阿片受体抗体 1ml
核蛋白4抗体(Ran结合蛋白4)抗体来源 Rabbit
克隆类型 polyclonal
交叉反应 Human, Mouse, Rat, Dog, Pig, Cow, Rabbit, Sheep
产品类型 一抗
研究领域 细胞生物 染色质和核信号 信号转导 表观遗传学
蛋白分子量 predicted molecular weight: 119- kDa
性 状 Lyophilized or Liquid
免 疫 原 KLH conjugated synthetic peptide derived from human Importin4/RanBP4
亚 型 IgG
纯化方法 affinity purified by Protein A
储 存 液 Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4
产品应用 WB=1:100-500 ELISA=1:500-1000 IP=1:20-100 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500
(石蜡切片需做抗原修复)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
Important Note This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
产品介绍 Functions in nuclear protein import as nuclear transport receptor. Serves as receptor for nuclear localization signals (NLS) in cargo substrates. Is thought to mediate docking of the importin/substrate complex to the nuclear pore complex (NPC) through binding to nucleoporin and the complex is subsequently translocated through the pore by an energy requiring, Ran-dependent mechanism. At the nucleoplasmic side of the NPC, Ran binds to the importin, the importin/substrate complex dissociates and importin is re-exported from the nucleus to the cytoplasm where GTP hydrolysis releases Ran. The directionality of nuclear import is thought to be conferred by an asymmetric distribution of the GTP- and GDP-bound forms of Ran between the cytoplasm and nucleus (By similarity). Mediates the nuclear import of RPS3A. In vitro, mediates the nuclear import of human cytomegalovirus UL84 by recognizing a non-classical NLS.
Function : Functions in nuclear protein import as nuclear transport receptor. Serves as receptor for nuclear localization signals (NLS) in cargo substrates. Is thought to mediate docking of the importin/substrate complex to the nuclear pore complex (NPC) through binding to nucleoporin and the complex is subsequently translocated through the pore by an energy requiring, Ran-dependent mechanism. At the nucleoplasmic side of the NPC, Ran binds to the importin, the importin/substrate complex dissociates and importin is re-exported from the nucleus to the cytoplasm where GTP hydrolysis releases Ran. The directionality of nuclear import is thought to be conferred by an asymmetric distribution of the GTP- and GDP-bound forms of Ran between the cytoplasm and nucleus (By similarity). Mediates the nuclear import of RPS3A. In vitro, mediates the nuclear import of human cytomegalovirus UL84 by recognizing a non-classical NLS.
Subunit : Binds with high affinity to RPS3A. The binding is coupled to RanGTP cycles. Binds to human cytomegalovirus UL84. Found in a cytosolic complex with ASF1A, ASF1B, CDAN1 and histones H3.1 and H4.
Subcellular Location : Cytoplasm (By similarity). Nucleus (By similarity).
核蛋白4抗体(Ran结合蛋白4)Similarity : Belongs to the importin beta family.
Contains 6 HEAT repeats.
Contains 1 importin N-terminal domain.
Database links : UniProtKB/Swiss-Prot: Q8TEX9.2
公司提供核蛋白4抗体(Ran结合蛋白4)价格绝对优势,欢迎新老客户来电垂询我公司优质抗体:核蛋白4抗体(Ran结合蛋白4)说明书及报价等。
核蛋白4抗体(Ran结合蛋白4)信息由上海抚生实业有限公司为您提供,如您想了解更多关于核蛋白4抗体(Ran结合蛋白4)报价、型号、参数等信息,欢迎来电或留言咨询。除供应核蛋白4抗体(Ran结合蛋白4)外,上海抚生实业有限公司还可为您提供Huh7.5人肝癌细胞、IM-9人多发性骨髓瘤细胞、JC 小鼠乳腺癌细胞等产品,公司有专业的客户服务团队,是您值得信赖的合作伙伴。