细胞纤毛内转运同源蛋白43抗体

以下为您提供的是细胞纤毛内转运同源蛋白43抗体的说明书,了解更多关于细胞纤毛内转运同源蛋白43抗体的英文名称,细胞纤毛内转运同源蛋白43抗体别名,细胞纤毛内转运同源蛋白43抗体规格,请看以下详细介绍.

英文名称  Anti-IFT43

中文名称  细胞纤毛内转运同源蛋白43抗体

别    名  C14orf179; ift43; IFT43_HUMAN; Intraflagellar transport protein 43 homolog.

浓    度  1mg/1ml

规 格  0.2ml/200μg    

抗体来源  Rabbit  

克隆类型  polyclonal

交叉反应  Human, Mouse, Rat, Dog, Pig, Cow, Horse, Sheep

细胞纤毛内转运同源蛋白43抗体的多样性：

抗体的异质性。抗体的组成极为复杂，是由成千上万、多种多样的免疫球蛋白（Ig）分子所组成。这些Ig分子在形状、大小、结构以及氨基酸的组成和排列上，既相似，又有差别。由于有差别，它们的电泳活性就有很大的变化。

因为抗体具有与抗原决定簇相对应的结合部位（抗原结合簇），所以抗体与抗原的结合具有特异性。另一方面，抗体本身是一种蛋白质，具有本身的氨基酸组成、排列和立体结构，对异种动物来说，它又是抗原。各类Ig都具有可用血清学方法检出的抗原特异性，它们表现出不同的血清学类型。

细胞纤毛内转运同源蛋白43抗体的相关产品:

Anti-α-AF/α-Afa α-L-阿拉伯呋喃糖苷酶抗体 0.1ml

Anti-α-Catenin/α-cats α-连环蛋白抗体（α链接素） 0.1ml

Anti-α-Synuclein   核突触蛋白/突触素-1抗体 0.1ml

Anti-β catenin/β-cats β-连环蛋白抗体（β链接素） 0.1ml

Anti-β-2-MG   鼠抗人β2微球蛋白抗体 0.1ml

产品类型  一抗    

研究领域  细胞生物 免疫学 信号转导 细胞骨架  

蛋白分子量  predicted molecular weight: 23kDa

性    状  Lyophilized or Liquid

免 疫 原  KLH conjugated synthetic peptide derived from human IFT43

亚    型  IgG

纯化方法  affinity purified by Protein A

储 存 液  Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4

产品应用   WB=1:100-500  ELISA=1:500-1000  IP=1:20-100  IHC-P=1:100-500  IHC-F=1:100-500  ICC=1:100-500  IF=1:100-500

（石蜡切片需做抗原修复）

 not yet tested in other applications.

 optimal dilutions/concentrations should be determined by the end user.  

保存条件  Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

Important Note  This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

产品介绍 IFT43 is a gene encodes a subunit of the intraflagellar transport complex A (IFT-A). IFT-A is a multiprotein complex that plays an important role in cilia assembly and maintenance by mediating retrograde ciliary transport. Mutations in this gene are a cause of cranioectodermal dysplasia-3 (CED3), also known as Sensenbrenner syndrome. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

Function : Component of IFT complex A (IFT-A) involved in retrograde ciliary transport along microtubules from the ciliary tip to the base.

Subunit : Component of the IFT complex A (IFT-A) complex (Probable). Interacts with WDR35/IFT121.

Subcellular Location : Cytoplasm, cytoskeleton. Note=Associated with microtubules.

DISEASE : Cranioectodermal dysplasia 3 (CED3) [MIM:614099]: A disorder primarily characterized by craniofacial, skeletal and ectodermal abnormalities. Clinical features include craniosynostosis, narrow rib cage, short limbs, brachydactyly, hypoplastic and widely spaced teeth, sparse hair, skin laxity and abnormal nails. Nephronophthisis leading to progressive renal failure, hepatic fibrosis, heart defects, and retinitis pigmentosa have also been described. Note=The disease is caused by mutations affecting the gene represented in this entry.

Similarity : Belongs to the IFT43 family.

细胞纤毛内转运同源蛋白43抗体Database links : UniProtKB/Swiss-Prot: Q96FT9.3