CDC23抗原(重组蛋白)
中文名称: CDC23 抗原(重组蛋白)
英文名称: CDC23 Antigen (Recombinant Protein)
别 名: cell division cycle 23; APC8; CUT23; ANAPC8
储 存: 冷冻(-20℃)
相关类别: 抗原
概述
Fusion protein corresponding to a region derived from 398-597 amino acids of human CDC23 |
技术规格
Full name: | cell division cycle 23 |
Synonyms: | APC8; CUT23; ANAPC8 |
Swissprot: | Q9UJX2 |
Gene Accession: | BC017713 |
Purity: | >85%, as determined by Coomassie blue stained SDS-PAGE |
Expression system: | Escherichia coli |
Tags: | His tag C-Terminus, GST tag N-Terminus |
Background: | The protein encoded by this gene shares strong similarity with Saccharomyces cerevisiae Cdc23, a protein essential for cell cycle progression through the G2/M transition. This protein is a component of anaphase-promoting complex (APC), which is composed of eight protein subunits and highly conserved in eukaryotic cells. APC catalyzes the formation of cyclin B-ubiquitin conjugate that is responsible for the ubiquitin-mediated proteolysis of B-type cyclins. This protein and 3 other members of the APC complex contain the TPR (tetratricopeptide repeat), a protein domain important for protein-protein interaction. |
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